| Chemical Engineering
“Edible fungi for Nutritive and Medicinal applications for anti-diabetic, anti-inflammatory and anti-Covid-19. Cost-effective process development for biodiesel.”
Production of therapeutic enzymes (L-Asparaginase and Lipase), Edible mycelial biomass and Bioactive metabolites from Fungal sps by Sub-Merged (SmF) and Solid-State Fermentation (SSF). Application of metabolites as a promising drug for Malnutrition, Anti-Cancer, and Anti-COVID-19. Fungal Lipase production and its Application for Biodiesel Synthesis. Detection of toxic analytes through hybrid Nanomaterial at ambient temperature.
1. Edible Fungi for Bioactive Compounds: Identification of ergosterol and gallic acid from fungal mycelium as a promising anti-COVID-19 metabolites. Purification of Biomolecules, Nutraceuticals and Recombinant Proteins.
2. Fungal Enzymes for Therapeutics: Collection, Isolation and Screening of fungal species. L-asparaginase for chemotherapy applications as well as in food processing industries. Scale-up studies and growth kinetics of L-asparaginase in bioreactor.
3. Lipase and Biodiesel Synthesis: Prosopis juliflora as a novel substrate to produce lipase by SSF. Developed to separate and quantify the methyl esters (MeP and MeO) in RP-HPLC for accurate analysis. Immobilized lipase used to waste cooking palm oil and found the biodiesel yield.
4. Sustainable Bio-Materials: Mycelium based material for applications in packaging and fabrics. Mycelium binds the agro-waste to obtain a rigid and compact composite material. Bio-Nano sensor, which can detect NO2 at room temperature with extreme precision.
1. Hamza, Arman., Ghanekar, Shreya., Kumar, D.S. Current trends in health-promoting potential and biomaterial applications of edible mushrooms for human wellness. Food Bioscience. 51, 102290 (2023).
2. Ashok, A., Doriya, K., Rao, J.V., Qureshi, A., Tiwari, A., Kumar, D.S. Microbes Producing L-asparaginase free of glutaminase and urease isolated from extreme locations of Antarctic soil and moss. Scientific Reports. 9, 1423 (2019).
3.Gopalakrishnan, L., Doriya, K., & Kumar, D. S. Moringa oleifera: A review on nutritive importance and its medicinal application. Food Science and Human Wellness, 5(2), 49-56 (2016).